Summary and highlights
Summary:
Dr. Fajgenbaum shares the story of a patient with Castleman disease who was near a hospice after not responding to all available therapies. Using an AI platform, clinicians identified a TNF inhibitor, adalimumabwhich had never been used for this condition. The patient was treated with this drug as a last-ditch effort, and his condition improved significantly, extending his life by more than a year. This example shows the incredible potential of AI-powered drug reuse to find solutions where none previously existed.
Key points to remember:
- AI can discover new uses for existing drugs, even for rare diseases that have exhausted all other treatment options.
- The AI-powered prediction identified a treatment that traditional research had overlooked, saving a patient’s life.
- AI offers clinicians new options for difficult-to-treat diseases by leveraging vast biomedical data.
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